CPSA Analytics 2019

Solutions for the Patient:
Building Communities One Patient at a Time

Meeting Program     Monday | Tuesday | Wednesday | Thursday

Updated April 22, 2019

 

Monday May 6

1:30 pm

Lobby

Registration Open

Meeting Room Lobby

WORKSHOPS


2:00 pm - 4:00 pm

Drake Ballroom

WORKSHOP 1
Technology for the Future - Innovations for the Patient

Workshop Leaders: Gary Valaskovic, New Objective; Neil Spooner, Spooner Bioanalytical Solutions; Mike Lee, Milestone Development Services


2:00 pm - 4:00 pm

Brandeis Room

WORKSHOP 2
The Future of Personalized Healthcare:
Integrated Solutions

Workshop Leaders: Alla Kloss, Sanofi, Amanda Berg,
New Objective; Emily Ehrenfeld, New Objective

4:30 pm - 5:30 pm

Drake Ballroom

Executive Roundtable

Where Technology and Solutions Meet the Patient

Discussion Leaders: Emily Ehrenfeld, New Objective; Mike Lee, Milestone Development Services

6:00 pm - 9:00 pm

Drake Ballroom

Opening Reception & Sponsor's Dinner

Opening Remarks
Emily Ehrenfeld, New Objective; Mike Lee, Milestone Development Services

CPSA Institute
Naidong Weng, Janssen Research & Development;
Neil Spooner, Spooner Bioanalytical Solutions

CPSA Charitable Foundation
Alla Kloss, Sanofi; Kathleen O'Sullivan-Fortin, ALD Connect; Kerry Hassell, Thermo Fisher Scientific; Brian Musselman, IonSense; Robyn Rourick, Genentech;
Emily Ehrenfeld, New Objective

Introducing ALD Connect:
Stronger When We're Together

Raising Awareness, Creating Community & Empowering Patients to Find a Cure for ALD
Florian Eichler, Harvard Medical School and Mass General Hospital, Kathleen O' Sullivan-Fortin, ALD Connect

The Voice of the Patients:
Living with ALD and the Promise of Innovation

Speakers: Jillian Smith and Matt Grew

 

Tuesday May 7

7:30 am - 8:30 am

Registration & Continental Breakfast

Meeting Room Lobby

8:30 am - 9:00 am

Drake Ballroom

Welcome & Opening Remarks

Mike Lee

Welcome
Mike Lee
Milestone Development Services

Amanda Berg

Format, Objectives, Opening Remarks
Amanda Berg
New Objective

Alla Kloss


Alla Kloss
Sanofi

9:00 am - 9:45 am

Drake Ballroom

Plenary Lecture

Plenary Speaker

Patient Centric Sampling and Analysis – Thinking Big About Small Samples
Neil Spooner
Spooner Bioanalytical Solutions

10:00 am - 11:45 am

Parallel Sessions

Drake Ballroom

Session 1: Symposium
Pushing the Boundaries of Sample Collection Near and Small: Patient Centric Sampling and Analysis

Discussion Leaders: Emily Ehrenfeld, New Objective and Neil Spooner, Spooner Bioanalytical Solutions

Small Patients Big Challenges
Enaksha Wickremsinhe, Eli Lilly and Company

Realizing Patient-Centric Blood Collection for Clinical Monitoring Applications
Erwin Berthier, Tasso Inc.

Probing Metabolic Heterogeneity Using MALDI-Imaging Mass Spectrometry
Shawn Davidson, Princeton University

Brandeis Room

Session 2: Colloquium
A Biomarker Odyssey:
The Search for Fluid-Based Indicators of Disease

Discussion Leader: Pablo Sardi, Sanofi

sRNA-FIND: An AI-Powered Discovery Platform to Subtype Disease
David W. Salzman, sRNAlytics

Comprehensive Exploratory Study to Identify Novel Biomarkers for Pompe Disease
Kelly George, Sanofi

Diagnostic Networks for Glycosylation Disorders: Fluxomic and Metabolomic Integration
Irwin Kurland, Albert Einstein College of Medicine

12:00 pm - 1:30 pm

Drake Ballroom

Sponsored Lunch & Roundtables

Biobanking Today:
Facebook, Crypto, and Artificial Intelligence

Discussion Leader: Brian Neman, Sanguine Biosciences

2:00 pm - 3:00 pm

Drake Ballroom

Sponsored Roundtables

Using Human Samples for Drug Discovery
Lian Rundell, Biorepository for Immunology (BRIM)
AbbVie Bioresearch Center

Event-Based, Same-Day, Longitudinal Sample Collection
Brian Neman, Sanguine Biosciences

3:15 pm - 4:45 pm

Parallel Sessions

Drake Ballroom

Session 3: Symposium
The Future Clinical Laboratory:
From Digitization to Automation to Data

Discussion Leaders: Amanda Berg, New Objective and Mike Lee, Milestone Development Services

The Future of the Modern Drug Discovery Laboratory
Hong Shen, Sanofi

Evolution in a Day: Microfluidics for Rapid, Label-Free Enzyme Screening at the Nanoliter Scale
Dan Holland-Moritz, University of Michigan

Next Generation Clinical Diagnostic Assays
Dobrin Nedelkov, Isoformix

5:30 pm - 9:00 pm

Drake Ballroom

Sponsored Hospitality & Evening Workshop

Imagine Summit

Featured Speaker:
Imagine Building Tomorrow Today
Dan Spellman, Merck

Market Overview and Trends, Solutions for the Patient
Dobrin Nedelkov, Isoformix

Center of Excellence-Princeton University/New Objective
Shawn Davidson, Princeton University

Partnerships - Precision Low Flow LC and Autosampler
Bernhard Nemec, Prolab Instruments

 

Wednesday May 8

7:30 am - 8:30 am

Registration & Continental Breakfast

Meeting Room Lobby

8:30 am - 10:15 am

Drake Ballroom

Symposium Session

Session 1: Symposium
Innovations in Medical Research for the Patient

Discussion Leader: Florian Eichler, Harvard Medical School

The Changing World of Rare Diseases:
Opportunities and Challenges
Florian Eichler, Harvard Medical School

Innovation in the Field of Batten's Disease
Susan Cotman, Harvard Medical School

Engineering the Skin as a Bioreactor:
Novel Gene Therapy Approaches
Anna Mandinova, MGH, Harvard Medical School

The Biology of Mucolipidosis Type IV and TRPML1-Related Disease
Yulia Grishchuk, Harvard Medical School

10:30 am - 12:00 pm

Parallel Sessions

Drake Ballroom

Session 2: Symposium
The Future of Personalized Healthcare:
Integrated Solutions

Discussion Leaders: Neil Spooner, Spooner Bioanalytical Solutions and Emily Ehrenfeld, New Objective

Patient Centric Sampling: Opportunities and Challenges
Melanie Anderson, Merck

The Disruptive Potential of Remote Sampling, the Patient and Beyond
Stephen Tomisich, Trajan Scientific & Medical

The Future of Microsampling
James Rudge, Neoteryx

Brandeis Room

Session 3: Colloquium
Analytical Innovations for 21st Century Drug Development

Discussion Leader: Monica Lane, Sanofi

Proteomics-based Prediction of HLA Peptides for Personalized Cancer Immunotherapy
Melissa Rotunno, Gritstone Oncology

Technological Advances for Rapid Plasma Biomarker Discovery and Qualification in Fabry Disease
Lisa Crawford, Sanofi-Genzyme

I am a Digital Disruptor
Harvey Lieberman, Sanofi-Genzyme



12:15 pm - 1:45 pm

Drake Ballroom

Sponsored Lunch & Roundtables

Getting Ahead of the Curve for Early Diagnosis of Preventable Diseases

Discussion Leaders: Jeremiah Tipton, BioTech and OMICSx Solutions, LLC and Neil Spooner, Spooner Bioanalytical Solutions

2:15 pm - 3:15 pm

Drake Ballroom

Sponsored Roundtables

The Future of Integrated Metabolomics:
Learning How to Plant in Rows

Discussion Leaders: Andrew Lee, IMCS, Abhishek Jha, Elucidata and Jeremiah Tipton, BioTech & OMICSx Solutions, LLC

Next Generation Diagnostic Tests
Jeremiah Tipton, BioTech & OMICSx Solutions, LLC

3:30 pm - 5:00 pm

Parallel Sessions

Drake Ballroom

Session 4: Symposium
Integrated Solutions for NanoFlow & MicroFlow LC-MS

Discussion Leaders: Amanda Berg, New Objective and Mike Lee, Milestone Development Services

Thinking Small: Minimizing Nano-HPLC Sample Volumes, Flow Rates, Delays, Carryover, and Software Complexity
Bernhard Nemec, ProLab

Automating Microextraction with INtip Chemistries Starting from Small Scale Experimental Designs to High Throughput Processes
Andrew Lee, IMCS

LC/MS-based Workflows for Targeted Protein Quantitation in Biopharmaceutical R&D: Automation, Micro and Nano Flow Chromatography, and Integrated Data Analytics
Dan Spellman, Merck

Brandeis Room

Session 5: Colloquium
Big Foot Club of CPSA: Very Small Samples, Very Big Data, New Frontiers in Proteomics, New Challenges for Bioinformatics

Discussion Leader: Harris Bell-Temin, Bristol-Myers Squibb

Adding a 4th Ion Mobility Dimension to Bottom Up Proteomics: Challenges and Rewards
Garry Kruppa, Bruker

Transformative Clinical Opportunities for Single-Cell Proteomics
Nikolai Slavov, Northeastern University

Bioinformatics, Biomarkers, Phenotypes, Therapeutics and Personalized Medicine to Advance Patient Health
Margarita Sordo, MGH, BWH, Harvard

5:30 pm - 6:30 pm

Social Hour & Exhibition

Munch, mix and mingle with our sponsors and vendors

Exhibit tables are open throughout the meeting, too.

6:30 pm - 8:00 pm

Drake Ballroom

Dinner, Announcements & Vendor Session

Announcements

CPSA Europe
Neil Spooner, Spooner Bioanalytical Solutions
Ismael Zamora, Molecular Discovery

CPSA Metabolomics
Abhishek Jha, Elucidata; Andrew Lee, ICMS

CPSA Shanghai
Min Liu, Merck
Naidong Weng, Janssen Research & Development

CPSA BRASIL
Carla Marshall-Waggett, New Objective

CPSA USA
Tim Olah, Merck
Neil Spooner, Spooner Bioanalytical Solutions

Program Chair Recognition

Emily Ehrenfeld, New Objective; Mike Lee, Milestone Development Services

Sponsor's Toast

Brian Neman, Sanguine Biosciences
Irwin Berthier, Tasso
Alla Kloss, Sanofi
Emily Ehrenfeld, New Objective


Vendor Session - "Five Minutes of Fame" (5MOF)

Vendors put their best foot forward in just 5-minutes

 

Thursday May 9

7:30 am - 8:30 am

Registration & Continental Breakfast

Meeting Room Lobby

8:30 am - 10:00 am

Parallel Sessions

Drake Ballroom

Session 1: Symposium
The Future of Personalized Healthcare: Mapping a Path Forward with Microscale Separations

Discussion Leaders: Amanda Berg, New Objective and Mike Lee, Milestone Development Services

Advanced Analytical Strategies for Proteomic and Glycomic Profiling of Limited Samples Using Ultra-Low-Flow Separations Coupled to Mass Spectrometry
Alexander Ivanov, Northeastern University

How, Why, Where and What We Should Measure in Clinical Trials
Arthur Combs, MC 10 Inc.

To Be Announced
Sue Abbatiello, Northeastern University

Brandeis Room

Session 2: Colloquium
Vendors for Innovation

Discussion Leader: Alla Kloss, Sanofi

Pure Mode or Mixed-Mode Chromatography?
Martin Gilar, Waters

PreON: An automated Platform for Enhanced Reproducibility & Minimal Hands On Time in the Processing of Clinical Samples
Russell Golson, PreOmics

IROA-based Workflow for Accurate Suppression-Corrected and Normalized Metabolomics Data Analysis
Chris Beecher and Felice de Jong, IROA Tech

10:15 am - 11:45 am

PARALLEL Sessions

Drake Ballroom

Session 3: Symposium
Frontiers in Innovation

Discussion Leader: Brian Musselman, IonSense

RNA Interference (RNAi) Therapeutics: ADME Properties and Bioanalytical Considerations
Jing-Tao Wu, Alnylam Pharmaceuticals

Approaches to Determine Drug Load on a Multimillion Dalton Water Insoluble Polymer Conjugate
Kim Alving, Sanofi

Direct Analysis of Sub-microliter Volumes of Urine and Oral Fluid: Examining Feasibility of Drug Detection without Chromatographic Separation
Brian Musselman, IonSense

Coated Blade Spray: Determination of Immunosuppressants in Whole Blood
German Augusto Gomez-Rios

Brandeis Room

Session 4: Colloquium
Innovative Approaches in Analysis of Pharmaceutical, Clinical and Biological Samples

Discussion Leader: Alexander Ivanov, Northeastern University

Development of a Fit-for-Purpose LC-MRM-MS Assay to Measure Prion Protein in Cerebrospinal Fluid
Eric Kuhn, Broad Institute

Searching for Parkinson's Biomarkers
Jarrod A. Marto, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School

High-Throughput Interactome Mapping to Identify Cancer Vulnerabilities
Wilhelm Haas, Harvard Medical School and Massachusetts General Hospital Cancer Center

12:00 pm - 1:30 pm

Drake Ballroom

Sponsored Lunch & Roundtables

To Be Announced

1:30 pm - 3:00 pm

Symposia Session

Drake Ballroom

Session 5: Symposium
New Approaches for Evaluation of Target Engagement

Discussion Leader: Kim Alving, Sanofi

Drug Distribution, Target Engagement and Off-Target Effects Revealed by Mass Spectrometry Imaging
Cristina Silvescu, Bruker Scientific

Chemical Tools for Selective Activity Profiling of Penicillin Binding Protein Class of Antibacterial Targets
Shabnam Sharifzadeh, University of Minnesota

Application of CETSA for Target Identification and Target Engagement
Clifford Phaneuf, Sanofi

Brandeis Room

Session 6: Colloquium
Analytical Solutions for New Therapeutic Modalities

Discussion Leader: Yelena Lubarskaya, Sanofi

Analytical Challenges for Gene Therapy: Navigating the Journey from Phase I/II to Commercial
Linda Engle, Biogen, Inc.

Analytical Toolbox Considerations for Early Molecular Screening of Next-Generation Antibodies
Monica Lane, Sanofi

Implementation of an Impurity Characterization Platform for RNAi Therapeutics
Roy Huang, Alnylam Pharmaceuticals

3:30 pm

Drake Ballroom

CLOSING REMARKS & ADJOURN

Amanda Berg, New Objective; Alla Kloss, Sanofi
Mike Lee, Milestone Development Services